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Menopausal symptoms such as hot flashes and night sweats can dramatically reduce quality of life for some women. Some women use hormone replacement therapy (HRT) to ease these symptoms. But research has shown that HRT increases breast cancer risk in women who haven’t been diagnosed. HRT also increases the risk of breast cancer coming back (recurrence) in women who have been diagnosed with the disease. HRT is not recommended for women who’ve been diagnosed with breast cancer. Undiagnosed women who have severe menopausal symptoms need to weigh the benefits of HRT against its risks.
Earlier research has shown that giving testosterone subcutaneously may ease several menopausal symptoms, including hot flashes, sleep problems, irritability, and fatigue. While testosterone is considered a male hormone because men have much higher levels, women do have testosterone. In men, testosterone is made by the testes. In women, the hormone is made by the ovaries and adrenal glands. Testosterone helps maintain:
- bone density
- fat distribution
- muscle strength and mass
- red blood cell production
- sex drive
- sperm production (in men only)
In women, the enzyme aromatase converts some testosterone to estradiol, a type of estrogen. Because HRT has been found to increase breast cancer risk, doctors believe that estradiol converted from testosterone could affect breast cancer risk. Read more here: http://www.breastcancer.org/research-news/20130928-8